Outcomes of Post-Traumatic Cardiac Injury: A 17-Year Retrospective Study at Tertiary Centers

Objective: To evaluate demographics, injury patterns, diagnostics, surgical strategies, and outcomes in cardiac trauma managed at tertiary hospitals, and to contextualize findings against contemporary…

Ethnic Influence on Internal Jugular Vein Diameter: A Comparative Ultrasonographic Study Between Turkish Citizens and Syrian Refugee-Migrant Adults

Purpose: This study aimed to investigate differences in internal jugular vein (IJV) diameter between adult Turkish citizens and Syrian refugee-migrant individuals, considering variables such…

Multi-Mechanistic Hepatoprotective Effects of Montelukast Against Doxorubicin-Induced Liver Injury in Rats

Aim: Despite its antineoplastic effect, doxorubicin (DOX) causes significant oxidative stress and cellular damage in the liver. This study aimed to demonstrate the oxidative…

Dual Inhibition and Optogenetic Regulation Targeting COX/5-LOX and TRPV1-Mediated Sensitization in the Neospinothalamic Pathway

The aim of this study is to elucidate the molecular sensitization mechanisms in the neospinothalamic pathway and to highlight that the limitations of current…

Laparoscopic abdominal cerclage in cervical insufficiency: single-centre outcomes

Objective: To evaluate surgical and obstetric outcomes following preconceptional laparoscopic abdominal cerclage (LAC) in women with complex cervical insufficiency. Materials and Methods: This retrospective…

Handgrip Strength in Individuals with Major Depressive Disorder: Associations with Psychosocial and Physical Factors

Objective: Major depressive disorder (MDD) is a heterogeneous clinical condition associated with impairments not only in mood and cognition but also in physical functioning.…

Association of Dexmedetomidine Use with Time to Intubation in Critically Ill COVID-19 Patients: A Retrospective Observational Study

Aim/Objective: Dexmedetomidine (DEX), a highly selective α2-adrenoceptor agonist, has sedative, analgesic, anxiolytic, and immunomodulatory properties that may provide benefits in critically ill patients with…

Comparison of Cost Analyses of Laryngeal Mask Airway and Endotracheal Tube Use in Anaesthesia Management: A Prospective Study

Objective/Background: This study aimed to compare the direct costs and clinical outcomes of endotracheal tube (ET) and laryngeal mask (LM) applications, which are widely…

Management of Cases of Intrauterine Fetal Demise: A Retrospective Analysis

Background: To evaluate the management process and short-term maternal outcomes of women managed for intrauterine fetal demise (IUFD) and to compare maternal outcomes according…

The Effect of Resveratrol in Alleviating Cadmium Induced Rat Ovarian Damage

Aim: Cadmium (Cd) exposure leads to severe histological damage (follicular atresia, granulosa cell degeneration) and increased oxidative stress in rat ovarian tissue. This study…

Predicting Functional Status in Adrenal Adenomas: The Role of Radiological Findings

Aim: The increasing use of imaging modalities has led to a higher detection rate of adrenal incidentalomas. Surgical treatment is recommended for hormonally active…

Analysis of the Relationship between Depressive Symptoms and Quality of Life in Menopausal Women

Aim: The present study evaluates depressive symptom levels in menopausal women and examines their impact on physical, psychological, and social quality of life. Methods:…

Age-Stratified Evaluation of ChatGPT Recommendations for Abnormal Uterine Bleeding: An Expert-Based Assessment of Guideline Adherence and Clinical Appropriateness

Background: Abnormal uterine bleeding (AUB) requires age-sensitive evaluation because endometrial hyperplasia or malignancy risk increases with age and after menopause. Large language models are…

Quality and Safety of ChatGPT Responses to Anesthesia-Related Patient Questions: An Expert Evaluation

Aim: Large language models such as ChatGPT are increasingly used by patients to obtain perioperative information. Given the complexity and potential risks associated with…

Salvage Superselective Vesical Artery Embolization for Intractable Hematuria Refractory to Conservative and Endoscopic Management: Angiographic Patterns and Short-Term Outcomes by Etiology

Background/Objective: Intractable bladder hematuria may persist despite continuous bladder irrigation and endoscopic hemostasis, exposing frail patients to repeated transfusions and the morbidity associated with…

Primary Gastric Extraosseous Osteosarcoma with Extensive Multivisceral Invasion: A Case Report

Introduction: Extraosseous osteosarcoma (ESOS) is a rare soft-tissue sarcoma that produces osteoid without anatomical relationship to the skeleton. Primary gastric ESOS is exceptionally rare…

The Impact of an Additional Osteotomy Maneuver for Nasal Bone Convexity on Let-Down Rhinoplasty

Objective: To evaluate the effect of an additional piezo-assisted transverse osteotomy on C-shaped nasal deformities in let-down rhinoplasty. Material and Methods: A retrospective review…

Effectiveness and Safety of Therapeutic Plasma Exchange in Intoxication Cases: A Single-Center Retrospective Study

Objective: This study aimed to retrospectively evaluate clinical characteristics, procedural parameters, complication rates, and mortality-related factors in patients who underwent therapeutic plasma exchange (TPE)…

Clinicopathological Features of Syringocystadenoma Papilliferum and Its Malignant Counterpart: A Single-Center Experience

Purpose: Syringocystadenoma papilliferum (SCAP) is a rare benign adnexal tumor with a distinctive histomorphology. Occasionally, there is a diagnostic difficulty, especially in separating it…

Predictive Value of Systemic Immune-Inflammation Index for Infectious Complications Following Transrectal Ultrasound-Guided Prostate Biopsy

Aim: This study aimed to evaluate the predictive value of the systemic immune-inflammation index (SII) for infectious complications following transrectal ultrasound-guided prostate biopsy. Materials…

Impact of Arthroscopes in the Diagnosis of the RAMP Lesion: 30° or 70° Arthroscope?

Aim: This study compared the diagnostic accuracy of 30° and 70° arthroscopes used through standard anterior portals for detecting complete and partial RAMP lesions…

Transversus Abdominis Plane Block Research in Türkiye: An Evaluation of National and International Databases

Aim/Objective: This study aimed to bibliometrically analyze scientific publications on transversus abdominis plane (TAP) block produced by Turkey-affiliated authors through Web of Science (WoS)…

The Analytical Performance of an Automated Urine Analyzer – Iriscell IQ200

Aim: To evaluate the analytical performance of the analyzer's urine parameter measurements and compare them with urine culture results. Methods: The study was undertaken…

Spontaneous Formation and Resolution of a Large Steinstrasse Without Renal Parenchymal Loss: A Case Report

Aim: We present a case of large-volume ureteral steinstrasse that formed and passed spontaneously from the ureter without medical expulsive therapy (MET) or ureteral…

Are AI Chatbots Ready for HoLEP Patient Education? A Comparative Evaluation of ChatGPT, Gemini, and Claude

Objective: To compare the quality, guideline concordance, and readability of HoLEP-related patient education responses generated by ChatGPT, Gemini, and Claude. Materials and Methods: Thirty…

Preoperative Hepatic Steatosis as a Postoperative Acute Renal Damage Predictor in Isolated Coronary Artery Bypass Grafting Surgery?

Aim: The aim of this study was to evaluate the prognostic effect of preoperative hepatic steatosis on the development of postoperative acute kidney injury…

Clinicopathological Factors Associated with Intravesical Recurrence and Survival After Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma

Aim: To evaluate clinicopathological factors and perioperative complications associated with intravesical recurrence-free survival (IVR-FS) and overall survival (OS) after radical nephroureterectomy (RNU) for upper…

Association of p16 Loss and EZH2 Overexpression with Clinicopathological Characteristics and Prognosis in Gastrointestinal Stromal Tumors

Aim: Gastrointestinal stromal tumors (GISTs) exhibit markedly heterogeneous clinical behavior that is not fully captured by conventional risk classification systems. This study aimed to…

Diagnostic and Therapeutic Impact of SpyGlass DS-Assisted Single-Operator Digital Cholangioscopy During ERCP

Aim: This study aimed to evaluate the technical success, diagnostic and therapeutic impact, safety profile, and long-term outcomes of SpyGlass DS-assisted single-operator digital cholangioscopy…

Comparison of Carboxyhemoglobin Levels, Pulmonary Functions, and Nicotine Dependence Among Smoking Healthcare Professionals in the Operating Theater

Objective: While the individual impacts of tobacco and surgical smoke are known, their combined effect on the respiratory health of healthcare professionals remains undocumented.…

Associations of Hyperuricaemia with Frailty, Probable Sarcopenia, and Sleep Quality in Older Adults

Background: This study investigated the associations of hyperuricaemia with subjective sleep quality, frailty, and probable sarcopenia in older adults. Methods: This retrospective cross-sectional study…

Short-Term Outcomes of Carpal Tunnel Release in Patients with CRPS-Like Symptoms

Introduction: Some patients diagnosed with complex regional pain syndrome (CRPS) may have an underlying peripheral nerve trigger, including mechanical irritation of the median nerve…

Comparison of Pain Intensity and Neuropathic Characteristics in Single-Level L4-L5 and L5-S1 Lumbar Disc Herniations

Introduction: Lumbar disc herniation is a common clinical condition in which pain severity and characteristics may differ according to the anatomical level involved. This…

Changes in Cesarean Section Rates Following a Multifaceted Institutional Obstetric Quality Improvement Strategy: A Robson Ten-Group Classification Analysis

Objective: To evaluate changes in overall and Robson group-specific cesarean section (CS) rates following implementation of a multifaceted institutional obstetric quality improvement strategy in…

Association Between Red Cell Distribution Width (RDW) and HbA1c in Non-Anemic Patients with Type 2 Diabetes Mellitus

Aim: Diabetes mellitus (DM) is a complex disease characterized by chronic hyperglycemia that leads to complications affecting the kidneys, eyes, peripheral nerves, and micro-…

Systemic Inflammatory and Immunonutritional Indices for Discriminating Ruptured From Non-Ruptured Endometriomas at Presentation: A Retrospective Study

Objective: Ruptured endometrioma is an uncommon but clinically important emergency that often mimics other causes of acute abdomen, making timely diagnosis challenging. This study…

Association Between Plasma Osmolality and Contrast-Induced Nephropathy in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

Objective: Contrast-induced nephropathy (CIN) is a clinically relevant complication of percutaneous coronary intervention (PCI), particularly in acute coronary syndrome (ACS). Calculated plasma osmolality (PO),…

Mild neurological symptoms in preeclampsia before cesarean delivery: A warning for intracranial hemorrhage

Preoperative TSH Levels as an Adjunctive Risk Factor for Malignancy in Thyroid Nodules: Our Single-Center Experience

Objective: To evaluate the association between preoperative thyroid-stimulating hormone levels and postoperative histopathological malignancy in patients undergoing thyroidectomy for thyroid nodules, and to compare…

Extended Bayram Holidays and Surgical Timing in Orthopaedic Fracture Patients: A Matched-Control Study, 2016–2025

Aims: To assess whether admission during Ramadan Bayram or Eid al-Adha was associated with surgical timing in orthopaedic fracture patients. Hospital stay, surgery within…

Hemodynamic Reclassification Under the 2022 Definition in Connective Tissue Disease-Associated Pulmonary Arterial Hypertension: A Single-Center Cohort Study

Introduction: The 2022 pulmonary hypertension guidelines lowered the hemodynamic thresholds for pulmonary hypertension and pulmonary arterial hypertension, potentially expanding the spectrum of connective tissue…

Diagnosis and Management of Ingested Foreign Bodies in Unusual Localizations: A Case Series

Background: This study aimed to evaluate the clinical presentations associated with ingested foreign bodies located in unusual regions of the gastrointestinal tract and to…

Intensive Care Management of Adult Intoxication Cases: A Retrospective Study

Objective/Rationale: To evaluate the demographic characteristics, clinical course, treatment processes, and prognostic factors associated with mortality in adult intoxication cases admitted to the intensive…

The Relationship Between Carcinoembryonic Antigen and Prognosis in Colorectal Cancer

Predicting ICU Admission and Length of Stay in Geriatric ED Patients: Comparison of Clinical Scores, Frailty and Comorbidity

Objective: To evaluate the association of commonly used clinical scores, frailty and comorbidity burden with intensive care unit(ICU) admission and ICU length of stay(LOS)…

Occupational Injuries Presenting to an Emergency Department Adjacent to a Large Organized Industrial Zone: Epidemiological Characteristics and Fracture-Related Factors

Objective: Emergency departments near industrial zones can support occupational-injury surveillance. We described presentations to the hospital closest to a large organized industrial zone and…

Association Between Preoperative Primary Tumor SUVmax on FDG PET/CT and High-Risk Pathological Features for the Prediction of Lymph Node Metastasis in Endometrial Cancer

Aim: To evaluate the association between preoperative primary tumor SUVmax on 18F-FDG PET/CT and lymph node metastasis, and to assess its relationship with high-risk…

Fragmented QRS: Electrophysiological Bases, Pathophysiological Mechanisms, and Clinical Prognostic Significance

Background: Fragmented QRS (fQRS) is characterized by morphological irregularities in ventricular depolarization on a standard 12-lead surface electrocardiogram (ECG) and is considered a non-invasive…

Evaluation of Oncologic Patients with Suspected Lesions on Planar Bone Scintigraphy Using SPECT/CT

Aim: This study aimed to evaluate the diagnostic accuracy of Single photon emission computed tomography/Computed tomography (SPECT/CT) to clinical management in oncologic patients with…

Intercostal Muscle Density as a Prognostic Imaging Marker in Isolated Blunt Thoracic Trauma

Aim: To investigate the value of intercostal muscle density measured at the primary trauma site in predicting subsequent thoracic injuries, unexpected injuries, and poor…

Risk Factors for Recurrent Febrile Urinary Tract Infection in Children with Vesicoureteral Reflux

Aim: Recurrent febrile urinary tract infection (UTI) in children with vesicoureteral reflux (VUR) is associated with renal scarring and long-term morbidity. This retrospective cohort…

Bone Quality and Osteoporosis in Shoulder Surgery: A Bibliometric Analysis of Research Trends (2010–2025)

Purpose. To map the literature on bone quality and osteoporosis in shoulder surgery published between 2010 and 2025 using bibliometric methods, describing publication and…

Comorbidities Are Not Contraindications to Free Flap Reconstruction in Elderly Patients with Advanced Head and Neck Cancer

Aim: Elderly patients with advanced head and neck cancer are often managed with non-surgical treatments due to concerns about comorbidities and perioperative risk, which…

Health Literacy and Patient Learning Needs Among Otolaryngology Patients: A Cross-Sectional Study

Aim: The aim of this study was to determine the levels of health literacy and patient learning needs among patients who had undergone otolaryngological…

Associations of Demographic and Menopause-Related Characteristics with SCORE2 Cardiovascular Risk Among Women Aged 45 to 55 Years: A Retrospective Analysis

Objectives: Menopause-related symptoms and hormonal changes may influence cardiovascular risk. We assessed demographic and menopause-related characteristics associated with SCORE2 risk in women aged 45–55…

Patient Selection for Locoregional Anesthesia in Pediatric Hand and Upper-Extremity Surgery: The Role of Age, Child Anxiety, and Parental Anxiety

Aim/Objective: The aim of this study was to identify the clinical and anxiety characteristics associated with the selection of locoregional versus general anesthesia in…

Association of Intraoperative Low-Dose Lidocaine Infusion with Postoperative Tramadol Requirement After Laparoscopic Cholecystectomy: A Retrospective Analysis

Aim: Intravenous lidocaine infusion has been proposed as an opioid-sparing adjunct in multimodal analgesia; however, its efficacy following laparoscopic cholecystectomy remains controversial. This study…

Indocyanine Green Fluorescence Angiography as a Navigational Adjunct in Focused Parathyroidectomy: Does It Contribute to Surgical Outcomes?

Introduction: Indocyanine green (ICG) fluorescence angiography enables real-time visualization of hypervascular parathyroid tissue and has shown promise as an intraoperative navigational tool. However, its…

The Effect of Online Cytology Education on Knowledge Levels: A Pretest and Posttest Study

Background: Dermatologic cytology is a rapid, inexpensive, and minimally invasive diagnostic method that can provide valuable information in the evaluation of various skin diseases.…

Etiology, AO/OTA Classification, and Clinical Distribution of Adult Distal Humerus Fractures at a Tertiary Trauma Center

Objective: Distal humerus fractures occur across a heterogeneous injury spectrum, ranging from low-energy fragility injuries to complex fractures caused by high-energy trauma. Studies examining…

Septic Shock Following Endoscopic Stone Surgery: Incidence, Clinical Characteristics, and Outcomes in a Retrospective Cohort Study

Aim/Objective: To evaluate the incidence, clinical characteristics, microbiological profile, and outcomes of septic shock requiring intensive care unit (ICU) admission following endoscopic stone surgery.…

Management of Isolated Mucormycosis on the Upper Extremity, A Rare Case Report

Objective: Mucormycosis is an invasive fungal infection characterized by rapid tissue necrosis and high mortality, particularly in immunocompromised patients. Upper extremity involvement is extremely…

Negative Pressure Wound Therapy in Infected and Complicated Wounds in Obstetrics and Gynecology: A Retrospective Comparative Study

Objective: To compare clinical characteristics, microbiological findings, and wound management outcomes between negative pressure wound therapy (NPWT) and conventional wound care in patients with…

Multidisciplinary Surgical Management of a Complex Thoracic Venous Malformation

Objective: Venous malformations are congenital low-flow vascular anomalies that may present significant therapeutic challenges when associated with extensive anatomical spread. This study presents the…

Severe Neurological and Systemic Adverse Events Following Cervical Epidural Steroid Injection: A Structured Review of Reported Clinical Cases, Anatomical Considerations, Pathophysiology, and Clinical Implications

Objective: To map out the clinical spectrum, timing, mechanisms, management, and outcomes of reported severe neurological and systemic adverse events following cervical epidural steroid…

Clinicopathological Features, Treatment Modalities, and Prognostic Factors of Leptomeningeal Carcinomatosis in Patients with Breast Cancer: A Single-Center Retrospective Analysis

Aim: Leptomeningeal metastasis (LM) from breast cancer carries a poor prognosis. We aimed to describe the clinicopathological features, diagnostic classification, and treatment patterns of…

Clinical and Hematological Factors Associated with Propofol Injection Pain: A Prospective Observational Study

Aim: This study investigated whether systemic inflammatory indices, including SII, NLR, and PLR, were associated with propofol injection pain and explored associations between clinical…

Prognostic Factors Associated with 90-Day Mortality Following Percutaneous Dilatational Tracheostomy: A Single-Center Retrospective Cohort Study

Background/Objective: Critically ill patients undergoing percutaneous dilatational tracheostomy (PDT) frequently require prolonged ventilatory support and have a high risk of adverse outcomes. This study…